Intelligence Research Today is a free monthly online journal that collates and summarizes the latest research about Intelligence, including details on iq, testing, nature vs nurture, cognition.

The correlation between striatal dopamine D2/D3 receptor availability and verbal intelligence quotient in healthy volunteers.

Guo JF, Kuang Yang Y, Tsing Chiu N, Lieh Yeh T, See Chen P, Lee IH, Lin Chu C

Department of Psychiatry, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

BACKGROUND: Although a correlation between the central dopaminergic system and intelligence may exist, the results from imaging studies remain inconclusive. The aim of this study was to explore the relationship between striatal dopamine D2/D3 receptor availability and verbal intelligence quotient (VIQ) using single photon emission computed tomography (SPECT). METHOD: Striatal D2/D3 receptor availability of 64 healthy subjects was determined with the [123I]iodobenzamide ([123I]IBZM) ligand. Intelligence quotients (IQs) of the subjects were measured by the Wechsler Adult Intelligence Scale--Revised (WAIS-R). RESULTS: In addition to age, left striatal D2/D3 receptor availability correlated positively with VIQ. In females, left striatal D2/D3 receptor availability was the only variable that correlated significantly with the similarities subtest of VIQ. CONCLUSIONS: There is a relationship between left striatal D2/D3 receptor availability and verbal intelligence, which varies, predominantly in males.

Published 15 March 2006 in Psychol Med, 36(4): 547-54.
Full-text of this article is available online (may require subscription).

© 2005-2008 Intelligence Research Today. All Rights Reserved.